Online Pharmacy Economics: Extortion at Home, Freedom Abroad?

Americans need and deserve the freedom to buy medications that are safe and affordable. This is not only true as a matter of right and wrong; it’s a public health issue since about 48 million Americans don’t fill prescriptions due to cost. Online pharmacies offer an important outlet for affordable medication. That’s the good news. The bad news is that some Americans are forced to use online pharmacies when they would rather not; and others who need them are discouraged from doing so. What’s going on here?

According to a recent L.A. Times article, “Consumer Confidential: Fewer choices on buying medications,” more and more Americans are being forced by pharmacy benefit managers (PBMs) to purchase their medication through domestic online pharmacies. Traditionally, PBMs acted as middlemen between health insurance companies, drug companies, and pharmacies. The third party relationship between PBM and pharmacy is deteriorating and the online pharmacies being forced upon Americans are often owned and operated by the PBM! This stands in contrast to the international marketplace.

When it comes to buying medication from Canada and other international pharmacies, despite its technical illegality, Americans feel free to choose which online pharmacy they wish to shop from. We write “technically” because, due to its internal policy guidance on enforcement priorities, the FDA does not appear to prosecute individuals for buying foreign, non-controlled medication for their personal use. Still, the FDA discourages Americans from using all non-US online pharmacies, even safe ones.

Independent studies have shown that credentialed international online pharmacies can and do offer a safe shopping experience through which Americans can best afford their medication. This takes the wind out of the sails of safety-related arguments put forward by the pharmaceutical industry — which profits greatly from high American drug prices — against personal drug importation. But there are other criticisms of personal drug importation that have to do with economics.

Foreign pharmacies are cheaper because other governments negotiate with pharmaceutical companies to control drug prices for all their citizens, something the U.S. government does not do.  Thus, personal drug importation is criticized for “importing” drug price controls and spoiling our “free market” in pharmaceuticals. But is our pharmaceutical market truly free?

In the LA Times article mentioned above, Jerry Lacy, who played Humphrey Bogart in “Play it Again Sam,” commented on his actor union’s arrangement with one of the largest PBM’s, Medco, which serves over 65 million people. “It’s like extortion…you do it their way or they won’t pay.” Mr. Lacy drew this conclusion after discovering he could only fill his prescriptions at the pharmacy of his choice twice at the insured (lower) price but then would have to buy from Medco’s online pharmacy or pay full (a higher) price elsewhere.

A letter to the editor by Chief Medical Officer of Express Scripts, another PBM, called “Letters: What Drugs Cost, and Why,” claims that PBM’s do provide choices. Well, maybe somewhat; but this is only partially true because the individual’s choice is not preserved. The employer or insurer chooses the option – not the individual. William Hale, in another letter to the LA Times editor, writes that he had to buy 90-day supplies for his medication from his PBM, even though his doctor would often change medication or dosage before the end of the 90 day supply. As a result, he has hundreds of unused pills and has ended up spending more than he would have if his PBM allowed him to purchase 30-day supplies from his local pharmacy. [For an excellent analysis about the free market for companies but not consumers read: “Inside The Secret World of Drug Company Rebates.”]

With foreign governments negotiating for lower prices in order to reign in government budgets, pharmaceutical companies seek higher profits from higher drug prices in the American “not-so-free” market..The American pharmaceutical market victimizes the millions of American consumers who are forced each year to pay more and more than their foreign counterparts for the same brand name medication or suffer the health consequences due to not taking prescribed medication. One way Americans seek justice is through international online pharmacies.

If considering online personal drug importation or any online pharmacy, experts have advised consumers to avoid online pharmacies that are not credentialed by reputable third parties, such as PharmacyChecker.com or VIPPS. But using common sense, Americans can and do make wise decisions about buying drugs online. For generic drugs, U.S. online pharmacies are often less expensive than non-US online pharmacies. The complete opposite is true for brand name drugs. Due to price competition among international online pharmacies (and of course foreign price controls), Americans can acquire from abroad the same medications sold here at an 80% discount.

By herding more of their members to their own pharmacies obviously PBMs can offer lower prices than local pharmacies; but this price reduction is not due to a “free market.”  The only pharmaceutical market that is meaningful to most Americans is the one that provides them a safe prescription medication at the lowest price. Ironically it is often non-US online pharmacies that offer them such freedom.

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In their blog yesterday, our friends at RxRights.org, an advocacy group dedicated to helping Americans afford needed prescription medication, applauded Senator McCain’s (R-AZ) amendment to the Food and Drug Administration Safety and Innovation Act to greater facilitate safe and legal personal drug importation of prescription medications from verified Canadian pharmacies. Despite Senator McCain’s emphasis on verification and product authenticity, and co-sponsor Al Franken’s (D-MN) statement on this bill’s role in reducing overall healthcare spending, the amendment failed in a 12-9 vote in the Senate Committee on Health, Education, and Labor and Pensions.

Those against the bill cited drug product safety issues and concerns over the anonymity of the internet. Most vociferously, Senator Barbara Mikulski (D-MD) claimed that even with the bill consumers would still not know where there drugs were coming from, failing to recognize or understand that the solution to this problem is written in the amendment, which calls for a verification process that would identify safe online pharmacies. Just such a program was adopted by Kathleen Sebelius, now Secretary of the Department of Health and Human Services, when she was Governor of Kansas.

For more on this vote, please visit RxRights.org.

Click here for a video of the committee hearing. Coverage of the amendment begins at 28:40.

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The main Op-Ed article in today’s New York Times, “The Wrong Way to Stop Fake Drugs,” calls for the legalization of personal drug importation from credentialed international online pharmacies, such as those approved in the PharmacyChecker.com Verification Program. Authored by Roger Bate, a resident scholar at American Enterprise Institute, the central message of the piece is that the technical ban on personal drug importation does not help the fight against counterfeit drugs but does discourage Americans from getting needed medication. We couldn’t agree more.

Dr. Bate offers evidence-based and compassionate approaches to help uninsured/underinsured Americans obtain medication at affordable prices and reduce the threat of counterfeit medication domestically and abroad. For more on this story see today’s press release

For the past year, Americans who buy medication from international online pharmacies have engaged through RxRights.org to help stop government actions that could block their online access to safe and affordable medication. Taking the cue from this latest op-ed, Americans should start asking their leaders to pass legislation directing the FDA to provide accurate information about online pharmacies. At the very least, the FDA should cease its categorical warning against all international online pharmacies for the simple reason that some are very safe and can help more Americans afford needed medications.

We looked at the top five brand name drugs by sales today to highlight the incredible price discrepancies between US pharmacy and international online pharmacy prices.

Price Comparisons for Lipitor, Advair Diskus, Nexium, Abilify, and Plavix

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Today we issued a press release showing that the most popular brand name asthma medications are on average 76% less when purchasing from the lowest-cost PharmacyChecker.com-verified online pharmacies than at U.S. bricks and mortar pharmacies. For example, a three month supply of Advair Diskus (250-50mcg/dose), a popular preventative medication, costs $947.97 at a bricks-and-mortar pharmacy in New York City. The same medicine, by the same manufacturer, costs $149.00, at a verified international online pharmacy – a savings of 84%. With such high prices domestically it’s no surprise Americans with asthma often find themselves going without needed treatments and ending up in emergency rooms.

A 2005 study sponsored by Kaiser Family Foundation, Harvard School of Public Health, and USA Today found that 44% of American households with an asthma sufferer are unable to follow prescribed treatments due to cost. According to the U.S. Centers for Disease Control and Prevention, 1.7 million Americans went to emergency rooms in 2009 due to their asthma conditions. The CDC attributed such hospitalizations to low adherence to asthma management strategies, which include taking preventative asthma medication. A study in the Journal of the American Medical Association last month reported that out-of-pocket costs for medicine were a factor in greater hospitalization rates among children with asthma in the U.S

The health benefits of products such as Advair Diskus, Flovent, and Singulair – preventative asthma medications –are sometimes difficult for patients to ascertain when they are not showing asthma symptoms. Unfortunately, because prices for these products are so high in the United States, Americans view skipping these medications as a way to save money and others simply can’t afford them. If more Americans could find these products at more reasonable prices, such as from verified international online pharmacies, then adherence would improve, leading to less ER visits, better overall health outcomes, and lower healthcare costs for all of us. And with more affordable asthma medication, trips to the grocery store will be less daunting.

For more on asthma medication prices, see the press release.

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As reported in DigitalJournal this past Wednesday, at a press conference in Keene, NH, Congressman Ron Paul (TX-14), Republican candidate for president, accused the pharmaceutical industry and the FDA of being in “bed together.” He derided their arrangement, characterized by a revolving door of people repeatedly switching jobs back and forth between the FDA and pharmaceutical industry, as collusion to reduce competition in the pharmaceutical marketplace, resulting in higher drug prices. When it comes to online pharmacies, personal drug importation and drug prices, Congressman Paul’s critique resonates all too loudly.

The pharmaceutical industry, through their main trade association Pharmaceutical Researchers and Manufacturers of America (PhRMA) has lobbied vigorously to keep safe personal drug importation illegal, and to scare Americans away through its media relations juggernaut and funding of the Partnership for Safe Medicine from buying safe and affordable medication online from Canada and other countries. PhRMA even commissioned the publication of a novel about a terrorist conspiracy – The Karasik Conspiracy in which terrorists attack Americans with bad drugs sold from Canada! This effort backfired and they pulled the plug on the publishing company, which then went ahead and published a different version of The Karasik Conspiracy novel in which a pharmaceutical giant poisons medications to protect its profits. (more…)

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A new study published by the National Bureau of Economic Research finds that pharmacies approved in the PharmacyChecker.com Verification Program sell safe medication and can help Americans achieve substantial savings. By filling 370 prescriptions through 41 online pharmacies and testing the authenticity of the medications received, independent researchers from the American Enterprise Institute in Washington, D.C. found no test failures among online pharmacies verified by third-party verifiers, such as PharmacyChecker.com.

Since all online pharmacies approved by PharmacyChecker.com – whether American or foreign – are licensed, require a prescription, and meet high standards of online pharmacy safety, the results of this study are not the least bit surprising. Past studies have shown the exact same results. Still, the FDA ignores the facts and continues a consumer education policy recommending that Americans completely avoid non-US online pharmacies. We believe the FDA’s policy is unethical and unfair.  More importantly, its policy is bad for the public health because less access to  affordable prescription drugs means fewer Americans will procure needed medications.

For more on this study see our news release.

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The New Healthcare Law Is No Panacea For The Drug Affordability Crisis In America

There is a drug affordability crisis in America. As we’ve reported, in 2010 48 million adults did not fill a prescription due to high drug costs. Perhaps surprisingly, in addition to millions of uninsured Americans, many Americans with insurance forgo prescription medication due to cost. Such insured Americans, unable to cover necessary medical costs, including medication, are often referred to as the underinsured. A previous study from 2004 by the American Society of Health-System Pharmacists reveals that 82.1% of those who restricted medication to due costs were actually insured. The picture is clear; underinsurance is a major issue in the battle to afford prescribed medication.

The Affordable Healthcare For America Act will help millions of Americans, including with their drug bills – but it is not a cure-all. It is uncertain how the new regulations will affect drug pricing. With drug price negotiations and cost reducing drug importation measures excluded from the healthcare act, and with millions of insured Americans currently struggling to pay high drug costs, what is to say newly insured people will not struggle to afford or go without prescribed medications?

Throughout the year PharmacyCheckerBlog will be following the research and predictions about drug affordability under the new law. Stay tuned…

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Are Americans Dying Because Drug Prices are Too High?

 Today, the AARP reported that brand name drug prices increased by 41% between 2006-2009, approximately three times the rate of inflation. In the New York Times article announcing the study, AARP refers to the price increases as “relentless”. The media often reports on studies about drug price increases because it’s an issue of great frustration for millions of Americans; and this blog has presented the facts on how tens of millions of Americans skip medication due to cost. But what are the public health ramifications of high drug costs? (more…)

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FDA Warns Patients and Healthcare Practices about Counterfeit Avastin

Counterfeit Avastin

According to the FDA, a counterfeit version of Avastin 400mg/16mL, a cancer treatment injectable medication, is being distributed in the United States, and “may have been purchased and used by some medical practices in the United States.” The fake drug “is labeled as Avastin, manufactured by Roche”, but it does not contain the medicine’s active ingredient, and is ineffective according to Roche. The counterfeit Avastin has “batch numbers that start with B6010, B6011 or B86017” and part of its label is written in French.

While it isn’t clear of how large the counterfeit supply is, the FDA has sent notice letters to 19 medical practices across the United States who may have administered the counterfeit drug to its patients, which could lead to adverse health effects. This counterfeit incident is different than one we reported on in 2010, when the FDA warned consumers about Generic Tamiful sold by an online pharmacy. In this case the Internet does not appear to play a role, rather the counterfeit drugs seem to have directly infiltrated the U.S. drug supply.

Price comparisons for Avastin are not available on PharmacyChecker.com, as its price listing participants do not offer this product for sale. Avastin is most often administered by a healthcare professional in a clinical setting not by the patient.

The reporting and disposal recommendations to healthcare professionals and patients by the FDA is as follows:

Medical practices that have obtained products from Volunteer Distribution and Quality Specialty Products should stop using them and contact the FDA. These products should be retained and securely stored. To report suspect counterfeit products and other suspect products obtained from Volunteer Distribution or QSP/Montana Health Care Solutions:

· Call FDA’s Office of Criminal Investigations (OCI) at 800-551-3989,

· Visit OCI’s Web site (www.accessdata.fda.gov/scripts/email/oc/oci/contact.cfm), or

· Email – DrugSupplyChainIntegrity@fda.hhs.gov

Healthcare professionals and patients are encouraged to report adverse events related to the use of suspect injectable cancer medications to the FDA’s MedWatch Safety Information and Adverse Event Reporting Program:

· Complete and submit the report Online: www.fda.gov/MedWatch/report.htm

· Download form or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178

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Candidate Rick Santorum Defends High Drug Prices In America

During a recent campaign appearance in front of a Tea Party crowd, as reported by ABC News, Republican presidential candidate Rick Santorum told a mother and her sick son that high drug costs are fair because they are determined by free market forces. It appears that Mr. Santorum doesn’t understand the crisis of prescription drug prices and that the market is failing to price prescription drugs within reach for 10s of millions of Americans.

According to ABC News, “Santorum told a large Tea Party crowd here that he sympathized with the boy’s case, but he also believed in the marketplace,” and that companies wouldn’t be making the life-saving drugs if they didn’t believe they would turn a profit doing so. The former senator from Pennsylvania seemed to be lecturing the American people when he said: “People have no problem paying $900 for an iPad…but paying $900 for a drug they have a problem with — it keeps you alive. Why? Because you’ve been conditioned to think health care is something you can get without having to pay for it.” (more…)

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